WebSee the list of drugs that interact with Simvastatin. Includes information on severity of interaction and the level of evidence for it. Simvastatin Interactions BNF NICE WebApr 1, 2024 · Drug Interactions . Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or …
Clarithromycin and simvastatin Interactions - Drugs.com
WebDrug interaction information. ... Both Ranolazine and Clarithromycin prolong the QT interval. Most manufacturers advise avoiding the use of two or more drugs that are associated with QT prolongation. ... Ranolazine slightly increases the exposure to Simvastatin. Manufacturer advises adjust Simvastatin dose. Severity: Moderate … WebAug 4, 2024 · liver problems - nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). Common simvastatin side effects may include: headache; constipation, nausea, stomach pain; or. cold symptoms such as stuffy nose, sneezing, sore throat. germany developed country
Evidence of Clinically Meaningful Drug-Drug Interaction With ...
WebApr 1, 2024 · Clarithromycin is used to treat bacterial infections in many different parts of the body. It is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori. This medicine is also used to prevent and treat Mycobacterium avium complex (MAC) infection. WebJan 9, 2024 · Drugs used to treat cholesterol ( statins ), such as simvastatin and lovastatin. Taking these drugs with clarithromycin may cause severe muscle problems. Sildenafil, tadalafil, and... WebJun 26, 2024 · Drug-drug interaction – where two medicines collide to produce either a desirable or adverse effect. For example – taking aspirin with NSAIDs increases the risk of bleeding. ... Simvastatin Lovastatin: ... Macrolides – such as clarithromycin – inhibit CYP enzymes that metabolize statins. Therefore, the risk of adverse effects of statins ... germany destination entry form