Cytoplasmic aconitate hydratase-like

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August undefined, 2024

WebPredicted to enable 4 iron, 4 sulfur cluster binding activity and aconitate hydratase activity. Predicted to be involved in tricarboxylic acid cycle. Predicted to be active in cytosol and mitochondrion. Is expressed in several structures, including adaxial cell; heart tube; musculature system; nervous system; and pronephric duct. Human ortholog(s) of this … WebJan 8, 2016 · This product is manufactured by BioVision, an Abcam company and was previously called K716 Aconitase Activity Colorimetric Assay Kit. K716-100 is the same size as the 100 test size of ab83459. Aconitase (aconitate hydratase; EC 4.2.1.3) is an iron-sulfur protein containing an [Fe4S4]2+ cluster that catalyzes the stereospecific …

Aconitate Hydratase - an overview ScienceDirect Topics

WebKEGG Orthology (KO) [BR:gsj00001] 09100 Metabolism 09101 Carbohydrate metabolism 00020 Citrate cycle (TCA cycle) 114372894 00630 Glyoxylate and dicarboxylate metabolism WebAug 1, 1988 · Abstract and Figures. This paper describes the characterization of aconitate hydratase (EC 4.2.1.3) in cytoplasmic and mitochondrial extracts from Ehrlich ascites … sims unable to start hatası

UniProt

WebCytoplasmic aconitate hydratase Kind protein Organism Humans Protein. Name UniProt ID; Cytoplasmic aconitate hydratase: P21399: Details: Drug Relations Drug Relations. … WebJul 27, 2011 · Cytoplasmic aconitate hydratase Curated EC number EC:4.2.1.3 ( UniProtKB ENZYME Rhea) By similarity Short names Aconitase Alternative names … WebSpecific Function. Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, … rctcbc.gov.uk/maincolss

Characterization of aconitate hydratase from …

WebThe activity of the iron-dependent enzyme cytosolic aconitase (c-aconitase) is increased by iron. The conversion of citrate to isocitrate by c-aconitase is the first step in a three … WebAconitase is an iron–sulfur protein that isomerizes citrate to isocitrate through the enzyme-bound intermediate cis -aconitate. The two-step reaction is reversible and involves dehydration followed by hydration. Although citrate is a symmetric molecule, aconitase works specifically on the OAA end of citrate, not the end derived from acetyl ... rctcbc half term holidaysWebNX_P21399 - ACO1 - Cytoplasmic aconitate hydratase - Localization. Bifunctional iron sensor that switches between 2 activities depending on iron availability (PubMed:1946430, PubMed:1281544, PubMed:8041788). Iron deprivation, promotes its mRNA binding activity through which it regulates the expression of genes involved in iron uptake, sequestration … rctcbc highways department

"WebMar 29, 2024 · cytoplasmic aconitate hydratase Names aconitase 1, soluble aconitate hydratase, cytoplasmic citrate hydro-lyase cytoplasmic aconitase cytosplasmic … " - Cytoplasmic aconitate hydratase-like

Cytoplasmic aconitate hydratase-like

WebSearch Result : 7756 hits. Entry KO len SW-score(margin) bits identity overlap best(all WebSep 21, 2008 · Data on the structure, functions, regulation of activity, and expression of cytosolic and mitochondrial aconitate hydratase isoenzymes of mammals are reviewed. The role of aconitate hydratase and structurally similar iron-regulatory protein in maintenance of homeostasis of cell iron is described. Information on modifications of the …

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WebIron and citrate are essential for the metabolism of most organisms, and regulation of iron and citrate biology at both the cellular and systemic levels is critical for normal physiology and survival. Mitochondrial and cytosolic aconitases catalyze the interconversion of citrate and isocitrate, and …

WebWe show that PP2A-B'γ physically interacts with the cytoplasmic form of aconitase, a central metabolic enzyme functionally connected with mitochondrial respiration, oxidative stress responses and regulation of cell death in plants. Furthermore, PP2A-B'γ impacts ROS homeostasis by controlling the abundance of specific alternative oxidase ... WebJul 30, 1999 · IRP1 is a cytoplasmic aconitase when it contains a [4Fe-4S] cluster and an RNA-binding protein after complete removal of the metal center by an unknown mechanism. Human IRP1, obtained as the pure recombinant [4Fe-4S] form, is an enzyme as efficient toward cis-aconitate as the homologous mitochondrial aconitase.

WebAconitase is an iron–sulfur protein that isomerizes citrate to isocitrate through the enzyme-bound intermediate cis -aconitate. The two-step reaction is reversible and involves … WebMar 3, 2024 · Area under the receiver operating characteristic curve (AUC) for cytoplasmic aconitate hydratase, argininosuccinate synthase, carbamoylphosphate synthase, fumarylacetoacetase, fructose-1,6-bisphosphatase 1 (FBP1) across cohorts achieved near complete separation (range: 0.94-0.99) of DO and HV. In addition, we show that FBP1, …

WebJan 4, 2024 · fumarate hydratase Antibody (J-13) is a mouse monoclonal IgG 2b κ, cited in 58 publications, provided at 100 µg/ml. raised against recombinant fumarate hydratase of human origin. recommended for detection of precursor mitochondrial and cytoplasmic mature chains of fumarate hydratase of human origin by WB, IP, IF, IHC (P) and ELISA.

WebAug 1, 1988 · This paper describes the characterization of aconitate hydratase (EC 4.2.1.3) in cytoplasmic and mitochondrial extracts from Ehrlich ascites tumor cells carried by BALB/C mice. The results show a ... rctcbc homefinderWebAconitate Hydratase. Aconitate hydratase (aconitase, EC4.2.1.3) is both an important Krebs cycle enzyme and a cytosolic iron sensor as described above. From: Nutrient … rctcbc.gov.uk planningWebDec 23, 2003 · Nevertheless, little is known regarding the response of aconitase to pro-oxidants within intact mitochondria. In the present study, we provide evidence that aconitase is rapidly inactivated and subsequently reactivated when isolated cardiac mitochondria are treated with H (2)O (2). Reactivation of the enzyme is dependent on the presence of the ... rctcbc fly tippingWebGene ID: 105431932, updated on 7-Sep-2024. Summary Other designations. cytoplasmic aconitate hydratase-like rctcbc mashWebImmunocytochemistry/ Immunofluorescence: Aconitase 1 Antibody [NBP1-87677] - Staining of human cell line U-2 OS shows localization to cytosol & mitochondria. Antibody staining is shown in green. Immunohistochemistry-Paraffin: Aconitase 1 Antibody [NBP1-87677] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells. rctcbc housingWebJul 12, 2024 · After the discovery in 1967 of plant glyoxysomes, aconitase, one the five enzymes involved in the glyoxylate cycle, was thought to be present in the organelles, and although this was found not to be the case around 25 years ago, it is still suggested in some textbooks and recent scientific articles. Genetic research (including the study of mutants … rctcbc covid grantWebCytoplasmic aconitate hydratase Kind protein Organism Humans Protein. Name UniProt ID; Cytoplasmic aconitate hydratase: P21399: Details: Drug Relations Drug Relations. DrugBank ID Name Drug group Pharmacological action? Actions Details; DB06757: Manganese: approved, nutraceutical: unknown: inhibitor: Details: sims university buy