Phosphatase and actin regulator
WebJul 23, 2024 · Phosphatase and actin regulator 3/nuclear scaffold-associated protein phosphatase 1-inhibiting protein (Phactr3/Scapinin) is an actin- and protein phosphatase 1 (PP1)-binding protein known to negatively regulate axon elongation. In this study, we examined the expression pattern of Phactr3/Scapinin in several tissues and investigated … WebApr 23, 2004 · The prototypical member of this family, phosphatase and actin regulator (phactr) 1 was a potent modulator of PP1 activity in vitro. Phactr-1 protein is selectively …
Phosphatase and actin regulator
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WebNov 25, 2024 · The PHACTR1 gene belongs to a family of proteins that interact with actin and play a role in the regulation of cell morphology and motility. PHACTR1 is expressed in … WebApr 23, 2004 · The prototypical member of this family, phosphatase and actin regulator (phactr) 1 was a potent modulator of PP1 activity in vitro. Phactr-1 protein is selectively expressed in brain, where high levels were found in cortex, hippocampus, and striatum, with enrichment of the protein at synapses.
WebDec 8, 2024 · This gene encodes a member of the phosphatase and actin regulator protein family. The encoded protein is associated with the nuclear scaffold in proliferating cells, and binds to actin and the catalytic subunit of protein phosphatase-1, suggesting that it functions as a regulatory subunit of protein phosphatase-1. WebPhosphatase and actin regulator 4 (Phactr4) is a newly discovered protein that inhibits protein phosphatase 1 and shows actin-binding activity. We previously found that Phactr4 is expressed in the neurogenic niche in adult mice, although its precise subcellular localization and possible function in …
WebPhosphatase. A ball and stick model of a phosphate anion. In biochemistry, a phosphatase is an enzyme that uses water to cleave a phosphoric acid monoester into a phosphate ion … WebOct 11, 2024 · Studies have found that the phosphatase actin regulatory factor 1 expression can be related to strok. Inhibiting phosphatase and actin regulator 1 expression is …
WebFeb 22, 2024 · It also connects the extracellular matrix to the actin cytoskeleton. (2) Ezrin functions as a regulator of G-protein-related proteins. (3) Ezrin acts as a scaffold protein which recruits proteins involved in signal transduction. (4) Ezrin anchors cyclic AMP-dependent protein kinases (A-kinases).
WebApr 11, 2024 · To examine whether PP1 directly dephosphorylates shootin1a, we performed an in vitro phosphatase assay using purified phosphorylated shootin1a. Phosphorylated shootin1a was purified by immunoprecipitation from calyculin A-treated HEK293T cells expressing shootin1a (Fig. S1 B), and then incubated with the catalytic subunit of PP1 or … small to big countriesWebAbstract Background: Some genetic association studies tried to investigate potential associations of phosphatase and actin regulator 1 (PHACTR1) polymorphisms with coronary artery disease (CAD). However, the results of these studies were not consistent. highway vehicle damage complaintWebJul 23, 2024 · Neuron-enriched phosphatase and actin regulator 3 (Phactr3)/ nuclear scaffold-associated PP1-inhibiting protein (Scapinin) regulates dendritic morphology via its protein phosphatase 1-binding domain - ScienceDirect Biochemical and Biophysical Research Communications Volume 528, Issue 2, 23 July 2024, Pages 322-329 small to caps in excelWebJun 10, 2014 · Translationally controlled tumor protein (TCTP), a repressor for Na,K-ATPase has been implicated in the development of systemic hypertension, as proved by TCTP-over-expressing transgenic (TCTP-TG) mice. Aorta of TCTP-TG exhibited hypercontractile response compared to that of non-transgenic mice (NTG) suggesting dys-regulation of … highway vehcile beaconWebPhactr1 (Phosphatase and actin regulator 1) is abundantly expressed in the central nervous system and considered to regulate various neuronal processes through the regulation of … highway vehicle hireWebWe further identified the protein phosphatase and actin regulator 1 (PHACTR1) as a downstream target of miR-584 and found that TGF-β-mediated inhibition of miR-584 leads to increased expression of … highway vehicle recovery 2020WebMay 1, 2024 · Protein phosphatase 1 (PP1) is a multifunctional enzyme with diverse roles in the nervous system, including regulation of syn-aptic activity and dendritic morphology. … small to from stamp